Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125726 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL2295428 | 0.98 | ALDH1A1 (0.41) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL146878 | 0.98 | ALDH1A1 (0.44) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL29496111 | 0.98 | ALDH1A1 (0.44) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL5107 | 0.98 | ALDH1A1 (0.44) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL10323632 | 0.98 | ALDH1A1 (0.44) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL29350037 | 0.98 | ALDH1A1 (0.44) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL356363 | 0.96 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL3416712 | 0.96 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TDP1HSD17B10TSHR | |
| SCHEMBL16180526 | 0.96 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-23 | — | — | US | claimed |
| EP-3632920-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | Univation Technologies, LLC (US) | 2020-04-08 | — | — | EP | claimed |
| US-20180141883-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | UNIVATION TECHNOLOGIES, LLC (US) | 2018-05-24 | — | — | US | claimed |
| WO-2014171931-A1 | GRAPHENE NANORIBBONS AS SEMICONDUCTORS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-10-23 | — | — | WO | claimed |
| JP-2011524383-A | — | — | 2011-09-01 | — | — | JP | claimed |
| US-20110118289-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | ROTTAPHARM S.P.A. (IT) | 2011-05-19 | — | — | US | claimed |
| EP-2315588-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | Rottapharm S.p.A. (IT) | 2011-05-04 | — | — | EP | claimed |
| WO-2009152868-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | ROTTAPHARM S.P.A. (IT) | 2009-12-23 | — | — | WO | claimed |
| WO-2021117767-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROARYLCARBOXAMIDE ACETIC ACID DERIVATIVE | 田辺三菱製薬株式会社 | 2021-06-17 | — | — | WO | disclosed |
| EP-3288953-B1 | BIS(AMINOPHENYLPHENOL) LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2021-01-06 | — | — | EP | disclosed |
| US-10793557-B2 | Sting agonist compounds | MERCK SHARP & DOHME CORP. (US) | 2020-10-06 | — | — | US | disclosed |
| US-10696641-B2 | Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-30 | — | — | US | disclosed |
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | UNIVATION TECHNOLOGIES, LLC (US) | 2020-06-23 | — | — | US | disclosed |
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| WO-2006103453-A1 | IN SITU GENERATED ASYMMETRIC PALLADIUM CATALYST AND USES THEREOF | IC INNOVATIONS LIMITED (GB) | 2006-10-05 | — | — | WO | disclosed |
| EP-0937077-B1 | PYRIDONE-FUSED AZABICYCLIC- OR CYTISINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN ADDICTION THERAPY | PFIZER (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005111047-A1 | 1-HETEROCYCLYL-1,5-DIHYDRO-PYRIDO[3,2-B]INDOL-2-ONES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-11-24 | — | — | WO | disclosed |
| US-6630467-B2 | Therapy for drug abuse | PFIZER INC. | 2003-10-07 | — | — | US | disclosed |
| US-20030065173-A1 | Pyridone-fused azabicyclic- or cytisine derivatives, their preparation and their use in addiction therapy | O'NEILL BRIAN T (US) | 2003-04-03 | — | — | US | disclosed |
| US-6235734-B1 | TOBACCO ADDICTION | PFIZER INC | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696641-B2 | Bis(aminophenylphenol) ligands and transition metal catalysts prepared therefrom | WASF2, WEE2, THEM6 | ALDH1A1 2023/4885CYP2A6 560/4885TDP1 3693/4885 |
| US-20110118289-A1 | 6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW MAO INHIBITORS AND IMIDAZOLINE RECEPTOR LIGANDS | OPRM1, OPRD1, HTR3C | ALDH1A1 285/4885CYP2A6 143/4885TDP1 2919/4885 |
| US-10793557-B2 | Sting agonist compounds | STING1, CGAS, IRF3 | ALDH1A1 4795/4885CYP2A6 3504/4885TDP1 518/4885 |
| US-10689314-B2 | Methods for preparing bridged bi-aromatic ligands | TYR, AOC2, BICRA | ALDH1A1 1187/4885CYP2A6 187/4885TDP1 2775/4885 |
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | WASF2, WEE2, PICALM | ALDH1A1 1801/4885CYP2A6 761/4885TDP1 2207/4885 |
| US-20030065173-A1 | Pyridone-fused azabicyclic- or cytisine derivatives, their preparation and their use in addiction therapy | CHRNA5, CHRNA4, CHRNA10 | ALDH1A1 488/4885CYP2A6 370/4885TDP1 45/4885 |
| US-20180141883-A1 | METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS | TYR, AOC2, BICRA | ALDH1A1 1187/4885CYP2A6 187/4885TDP1 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.