Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544377 | 0.74 | CHRNB4 (0.43) | CHRNB4CHRNA3KDM1AKDM1B | |
| SCHEMBL7357341 | 0.73 | CHRNB4 (0.41) | CHRNB4CHRNA3KDM1AKDM1BCHRNB2 | |
| SCHEMBL5341308 | 0.73 | KDM1A (0.57) | KDM1AKDM1B | |
| SCHEMBL7329321 | 0.73 | KDM1A (0.57) | KDM1AKDM1B | |
| SCHEMBL956736 | 0.73 | CHRNB4 (0.41) | CHRNB4CHRNA3KDM1AKDM1BCHRNB2 | |
| SCHEMBL10486425 | 0.73 | CHRNB4 (0.41) | CHRNB4CHRNA3KDM1AKDM1BCHRNB2 | |
| SCHEMBL14284253 | 0.73 | KDM1A (0.57) | KDM1AKDM1B | |
| SCHEMBL7329314 | 0.73 | KDM1A (0.57) | KDM1AKDM1B | |
| SCHEMBL5704636 | 0.73 | KDM1A (0.57) | KDM1AKDM1B | |
| SCHEMBL9442858 | 0.72 | CHRNB4 (0.38) | CHRNB4CHRNA3KDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667353-B1 | Glycopeptide antibiotic derivatives | LILLY CO ELI (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6518243-B1 | Desleucyl glycopeptide antibiotics and methods of making same | TRUSTEES OF PRINCETON UNIVERSITY | 2003-02-11 | — | — | US | disclosed |
| EP-1016670-A1 | Glycopeptide antibiotic derivatives | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| US-5977062-A | ACTIVE AGAINST ANTIBIOTIC RESISTANT BACTERIA | ELI LILLY AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |