Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.43 |
| ▸ | GABRP | O00591 | 7/20 | 0.43 |
| ▸ | GABRD | O14764 | 7/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.43 |
| ▸ | GABRE | P78334 | 7/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927457 | 0.84 | GABRP (0.55) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10333583 | 0.76 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7069038 | 0.76 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7027170 | 0.74 | GABRP (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7667394 | 0.74 | GABRP (0.62) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7027165 | 0.74 | GABRP (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7248733 | 0.73 | GABRB3 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7027131 | 0.73 | GABRB3 (0.37) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7707155 | 0.72 | GABRP (0.60) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL8660906 | 0.72 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518296-B1 | For controlling at least one pest selected from the group consisting of insects, arachnids and nematodes | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-11 | — | — | US | disclosed |
| EP-1084111-A1 | SUBSTITUTED 3-THIOCARBAMOYLPYRAZOLES | Bayer Aktiengesellschaft (DE) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062886-A1 | SUBSTITUTED 3-THIOCARBAMOYLPYRAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-09 | — | — | WO | disclosed |