Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924027 | 0.89 | L3MBTL1 (0.47) | GPR119USP30PDE4BPRMT5WDR77 | |
| SCHEMBL6925099 | 0.89 | USP30 (0.48) | GPR119JAK2JAK1USP30PDE4B | |
| SCHEMBL6926570 | 0.87 | PDE4B (0.47) | GPR119JAK2JAK1USP30PDE4B | |
| SCHEMBL6929071 | 0.85 | USP30 (0.53) | GPR119JAK2JAK1USP30HTT | |
| SCHEMBL6925955 | 0.84 | GPR119 (0.48) | GPR119JAK2JAK1USP30PDE4B | |
| SCHEMBL18295360 | 0.82 | GPR119 (0.50) | GPR119JAK2JAK1USP30PDE4B | |
| SCHEMBL16814814 | 0.81 | USP30 (0.49) | GPR119JAK2JAK1USP30HRH1 | |
| SCHEMBL16792796 | 0.81 | USP30 (0.49) | GPR119JAK2JAK1USP30HRH1 | |
| SCHEMBL15375880 | 0.79 | USP30 (0.55) | GPR119JAK2JAK1USP30STS | |
| SCHEMBL15377844 | 0.79 | USP30 (0.55) | GPR119JAK2JAK1USP30STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515142-B2 | Intermediates of aromatic amidine derivatives which have anticoagulation action | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-05-23 | — | — | US | disclosed |
| US-6337405-B1 | MULTISTAGE REACTION OF PYRROLE SUBSTITUTED WITH SULFONATE GROUPS AND HYDROXYPHENYLACETIC ACID | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6252088-B1 | COUPLING A NITRILE CONTAININ NAPHTHALENE COMPOUND WITH A COMPOUND CONTAINING PROPIONIC ACID GROUP | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0936215-A1 | PROCESS FOR PREPARING 2-PHENYL-3-NAPHTHYLPROPIONIC ACID DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020062033-A1 | Process for preparing 2-phenyl-3-naphthylpropionic acid derivatives | PROC, F12, F2 | GPR119 4825/4885JAK2 3515/4885JAK1 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.