Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881405 | 1.00 | GAA (0.52) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| Hydrochloric Acid SCHEMBL15201265 | 0.99 | GAA (0.51) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL18710626 | 0.85 | ESR1 (0.54) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL21092645 | 0.85 | ESR1 (0.54) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL22251574 | 0.85 | ESR1 (0.54) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL18155287 | 0.85 | ESR1 (0.54) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL18710627 | 0.82 | ESR1 (0.52) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL24093821 | 0.81 | ESR1 (0.49) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL22251644 | 0.81 | ESR1 (0.54) | GAAALDH1A1KDM4EL3MBTL1ESR1 | |
| SCHEMBL14769640 | 0.81 | ESR1 (0.54) | GAAALDH1A1KDM4EL3MBTL1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261584-A4 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | MERCK & CO INC (US) | 2003-06-18 | — | — | EP | claimed |
| EP-1261584-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | Merck & Co., Inc. (US) | 2002-12-04 | — | — | EP | claimed |
| US-6479667-B2 | 2S-CIS-3-(((4-MERCAPTO-2-PYRROLIDINYL) CARBONYL)-AMINO)BENZOIC ACID AND SALTS AND SOLVATES ARE INTERMEDIATES IN THE SYNTHESIS OF CARBAPENEM COMPOUNDS | MERCK & CO., INC. | 2002-11-12 | — | — | US | claimed |
| US-20020062032-A1 | Crystalline forms of antibiotic side chain intermediates | MERCK & CO., INC. | 2002-05-23 | — | — | US | claimed |
| WO-2001064636-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | MERCK & CO., INC. (US) | 2001-09-07 | — | — | WO | claimed |
| EP-0998457-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | Merck & Co., Inc. (US) | 2000-05-10 | — | — | EP | claimed |
| US-5965747-A | CHEMICAL INTERMEDIATE FOR CARBAPENEM ANTIBIOTICS; STABILITY AND PURITY | MERCK & CO., INC. (US) | 1999-10-12 | — | — | US | claimed |
| WO-1999002492-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | MERCK & CO., INC. (US) | 1999-01-21 | — | — | WO | claimed |
| WO-2023138341-A1 | SYNTHESIS METHOD FOR ERTAPENEM SODIUM | 深圳市海滨制药有限公司 | 2023-07-27 | — | — | WO | disclosed |
| WO-2013121279-A2 | PROCESS TO PREPARE ERTAPENEM | AUROBINDO PHARMA LIMITED (IN) | 2013-08-22 | — | — | WO | disclosed |
| WO-2013121279-A2 | PROCESS TO PREPARE ERTAPENEM | AUROBINDO PHARMA LIMITED (IN) | 2013-08-22 | — | — | WO | disclosed |
| WO-2009150630-A2 | PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC COMPOSITION | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-17 | — | — | WO | disclosed |
| US-RE40794-E1 | Crystalline forms of carbapenem antibiotics and methods of preparation | MERCK & CO., INC. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-1261584-A4 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | MERCK & CO INC (US) | 2003-06-18 | — | — | EP | disclosed |
| EP-0998457-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | Merck & Co., Inc. (US) | 2000-05-10 | — | — | EP | disclosed |
| EP-0998457-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | Merck & Co., Inc. (US) | 2000-05-10 | — | — | EP | disclosed |
| US-5965747-A | CHEMICAL INTERMEDIATE FOR CARBAPENEM ANTIBIOTICS; STABILITY AND PURITY | MERCK & CO., INC. (US) | 1999-10-12 | — | — | US | disclosed |
| US-5965747-A | CHEMICAL INTERMEDIATE FOR CARBAPENEM ANTIBIOTICS; STABILITY AND PURITY | MERCK & CO., INC. (US) | 1999-10-12 | — | — | US | disclosed |
| WO-1999002492-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | MERCK & CO., INC. (US) | 1999-01-21 | — | — | WO | disclosed |
| WO-1999002492-A1 | CRYSTALLINE FORMS OF ANTIBIOTIC SIDE CHAIN INTERMEDIATES | MERCK & CO., INC. (US) | 1999-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020062032-A1 | Crystalline forms of antibiotic side chain intermediates | ABAT, CRYAB, CRYAA | GAA 774/4885ALDH1A1 1375/4885KDM4E 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.