SCHEMBL6929134

SCHEMBL6929134

CCC#CCOS(=O)(=O)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.47
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA9 Q16790 3/20 0.40
PRSS1 P07477 3/20 0.40
PRSS2 P07478 3/20 0.40
PRSS3 P35030 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 2/20 0.40
FAAH O00519 1/20 0.40
ELANE P08246 1/20 0.40
PRTN3 P24158 1/20 0.40
CA5A P35218 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.39
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28852658 0.78 KMT2A (0.57) KMT2ACA1CA2CA9PRSS1
SCHEMBL354454 0.78 KMT2A (0.57) KMT2ACA1CA2CA9PRSS1
SCHEMBL8756134 0.77 KMT2A (0.52) KMT2ACA1CA2CA9PRSS1
SCHEMBL11747445 0.77 KMT2A (0.52) KMT2ACA1CA2CA9PRSS1
SCHEMBL2383968 0.75 KMT2A (0.53) KMT2ACA1CA2CA9PRSS1
SCHEMBL29482067 0.75 KMT2A (0.53) KMT2ACA1CA2CA9PRSS1
SCHEMBL9309031 0.74 KMT2A (0.61) KMT2ACA1CA2CA9PRSS1
SCHEMBL6114729 0.74 KMT2A (0.61) KMT2ACA1CA2CA9PRSS1
SCHEMBL28243335 0.74 KMT2A (0.52) KMT2ACA1CA2CA9PRSS1
SCHEMBL7060572 0.72 ALDH1A1 (0.56) KMT2ACA1CA2CA9PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1218333-A4 ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS WOMENS & CHILDRENS HOSPITAL (AU) 2003-07-09 EP disclosed
EP-1218333-A1 ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS WOMEN'S AND CHILDREN'S HOSPITAL (AU) 2002-07-03 EP disclosed
WO-2001021575-A1 ANTI-INFLAMMATORY NITRO- AND THIA- FATTY ACIDS WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE (AU) 2001-03-29 WO disclosed