Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3183897 | 0.81 | — | — | |
| SCHEMBL28000485 | 0.76 | ALDH1A1 (0.41) | CA1CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL28606229 | 0.72 | THRB (0.44) | TSHR | |
| SCHEMBL7511905 | 0.72 | FFAR3 (0.33) | — | |
| SCHEMBL28128807 | 0.68 | CA1 (0.44) | CA1TSHR | |
| SCHEMBL3261388 | 0.68 | CHRM1 (0.42) | CA1CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL29059313 | 0.67 | CA1 (0.50) | CA1TSHR | |
| SCHEMBL8853585 | 0.67 | CA1 (0.41) | CA1CYP3A4TSHR | |
| SCHEMBL3230815 | 0.66 | HSD17B10 (0.39) | CA1CYP3A4TSHRNFKB1NPSR1 | |
| SCHEMBL28861680 | 0.66 | CA1 (0.48) | CA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |