Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511905 | 0.76 | FFAR3 (0.33) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28392866 | 0.74 | ALDH1A1 (0.44) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL23529421 | 0.74 | ALDH1A1 (0.48) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28606229 | 0.72 | THRB (0.44) | ALDH1A1 | |
| SCHEMBL5861522 | 0.71 | ALDH1A1 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27821923 | 0.71 | ALDH1A1 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2948698 | 0.71 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL23660530 | 0.70 | ALDH1A1 (0.37) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3747090 | 0.70 | ALDH1A1 (0.37) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Ammonia Solution, Strong SCHEMBL6537990 | 0.70 | ALDH1A1 (0.37) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |