SCHEMBL69292

SCHEMBL69292

COC(=O)c1cccc2c1C(=O)c1cccc(C(=O)OC)c1C2=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
MITF O75030 1/20 0.61
NPC1 O15118 1/20 0.58
PTPRC P08575 1/20 0.58
TSHR P16473 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
MEN1 O00255 1/20 0.57
HTT P42858 1/20 0.57
MAPK10 P53779 1/20 0.57
KMT2A Q03164 1/20 0.57
PTK2B Q14289 1/20 0.57
NCOA1 Q15788 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57
ALDH1A1 P00352 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
PDK2 Q15119 1/20 0.51
THRB P10828 1/20 0.51
LMNA P02545 3/20 0.50
SLC6A4 P31645 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8757428 0.95 MAPT (0.69) MAPTMITFNPC1PTPRCTSHR
SCHEMBL6760793 0.94 MAPT (0.59) MAPTMITFNPC1PTPRCTSHR
SCHEMBL21840821 0.91 NPC1 (0.71) MAPTMITFNPC1PTPRCTSHR
SCHEMBL2879389 0.87 MAPT (0.65) MAPTMITFNPC1PTPRCTSHR
SCHEMBL30393962 0.87 MAPT (0.65) MAPTMITFNPC1PTPRCTSHR
SCHEMBL70816 0.86 TSHR (0.62) MAPTMITFNPC1PTPRCTSHR
SCHEMBL70284 0.86 MAPT (0.67) MAPTMITFPTPRCTSHRSMN1; SMN2
SCHEMBL7540373 0.85 ALDH1A1 (0.56) MAPTMITFNPC1PTPRCTSHR
SCHEMBL13021518 0.82 MAPT (0.58) MAPTMITFPTPRCTSHRSMN1; SMN2
SCHEMBL7210611 0.81 MAPT (0.50) MAPTMITFNPC1PTPRCTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 MAPT 1923/4885MITF 513/4885NPC1 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.