SCHEMBL70816

SCHEMBL70816

COC(=O)c1cccc2c1-c1c(C(=O)OC)cccc1-2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
MAPT P10636 2/20 0.62
MEN1 O00255 1/20 0.62
HTT P42858 1/20 0.62
MAPK10 P53779 1/20 0.62
KMT2A Q03164 1/20 0.62
PTK2B Q14289 1/20 0.62
NCOA1 Q15788 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
NCOA3 Q9Y6Q9 1/20 0.62
PDK2 Q15119 1/20 0.55
LMNA P02545 1/20 0.55
PTPRC P08575 1/20 0.54
ALDH1A1 P00352 1/20 0.53
CFTR P13569 1/20 0.53
HSD17B10 Q99714 1/20 0.53
SLC6A3 Q01959 5/20 0.53
SLC6A4 P31645 3/20 0.53
KDM4E B2RXH2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70284 0.91 MAPT (0.67) TSHRMAPTMEN1HTTMAPK10
SCHEMBL69292 0.86 MAPT (0.61) TSHRMAPTMEN1HTTMAPK10
SCHEMBL21840821 0.85 NPC1 (0.71) TSHRMAPTMEN1HTTMAPK10
SCHEMBL6760793 0.84 MAPT (0.59) TSHRMAPTMEN1HTTMAPK10
SCHEMBL15008455 0.83 MYC (0.61) TSHRMAPTMEN1HTTMAPK10
SCHEMBL3576571 0.83 CA1 (0.59) TSHRMAPTMEN1HTTMAPK10
SCHEMBL69464 0.82 SLC6A3 (0.67) TSHRMAPTMEN1HTTMAPK10
SCHEMBL12602808 0.82 MAPT (0.57) TSHRMAPTMEN1HTTMAPK10
SCHEMBL2879389 0.81 MAPT (0.65) TSHRMAPTMEN1HTTMAPK10
SCHEMBL8757428 0.81 MAPT (0.69) TSHRMAPTMEN1HTTMAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TSHR 3263/4885MAPT 1923/4885MEN1 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.