Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406691 | 0.92 | KMT2A (0.37) | KMT2AEPHX2UBE2MDCUN1D1MEN1 | |
| SCHEMBL3410353 | 0.88 | KMT2A (0.35) | KMT2AEPHX2UBE2MDCUN1D1MEN1 | |
| SCHEMBL3406660 | 0.87 | KMT2A (0.34) | KMT2AEPHX2MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3407264 | 0.86 | KMT2A (0.39) | KMT2AUBE2MDCUN1D1MEN1ALDH1A1 | |
| SCHEMBL3405770 | 0.84 | KMT2A (0.37) | KMT2AUBE2MDCUN1D1MEN1ALDH1A1 | |
| SCHEMBL3403716 | 0.82 | MLYCD (0.32) | KMT2A | |
| SCHEMBL3410575 | 0.81 | POLB (0.37) | KMT2AEPHX2MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3407755 | 0.79 | GPR119 (0.34) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3405278 | 0.77 | SMN1; SMN2 (0.36) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3404273 | 0.77 | KMT2A (0.35) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-A2 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-12-17 | — | — | EP | claimed |
| WO-2002066035-A2 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-29 | — | — | WO | claimed |