Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545046 | 0.82 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL23531037 | 0.77 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL6842515 | 0.75 | TSHR (0.31) | TSHRALDH1A1 | |
| SCHEMBL2058215 | 0.72 | ALDH1A1 (0.32) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL1243041 | 0.69 | MEN1 (0.44) | TSHRALDH1A1LMNAMEN1THRB | |
| SCHEMBL28355332 | 0.69 | MEN1 (0.44) | TSHRALDH1A1LMNAMEN1THRB | |
| SCHEMBL79662 | 0.69 | ALDH1A1 (0.33) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL79154 | 0.68 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| Bromide SCHEMBL29074036 | 0.68 | — | — | |
| SCHEMBL14252611 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185257-A4 | TREATMENT OF ACNE USING LIPOIC ACID | PERRICONE NICHOLAS V (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6365623-B1 | ANTISCARRING | N.V. PERRICONE LLC | 2002-04-02 | — | — | US | disclosed |
| EP-1185257-A2 | TREATMENT OF ACNE USING LIPOIC ACID | PERRICONE, Nicholas V (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001049250-A2 | TREATMENT OF ACNE USING LIPOIC ACID | PERRICONE NICHOLAS V (US) | 2001-07-12 | — | — | WO | disclosed |