Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355332 | 1.00 | MEN1 (0.44) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL10495638 | 0.96 | LMNA (0.46) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL7525390 | 0.81 | OPRM1 (0.42) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL29078680 | 0.78 | MEN1 (0.38) | MEN1KMT2AHTTMAPTTHRB | |
| Dodecane SCHEMBL11481051 | 0.74 | MEN1 (0.54) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL16389829 | 0.74 | LMNA (0.48) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL7375060 | 0.74 | LMNA (0.46) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL6366837 | 0.74 | LMNA (0.46) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL755149 | 0.73 | PSMD14 (0.42) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL10951541 | 0.73 | PSMD14 (0.42) | MEN1KMT2AHTTMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459575-B2 | HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS | ADDIVANT SWITZERLAND GMBH (CH) | 2018-07-25 | — | — | EP | disclosed |
| EP-2459575-B1 | HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS | ADDIVANT SWITZERLAND GMBH (CH) | 2014-12-17 | — | — | EP | disclosed |
| EP-2459575-A2 | HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS | Chemtura Corporation (US) | 2012-06-06 | — | — | EP | disclosed |
| US-8048946-B2 | Hydrolytically stable phosphite compositions | CHEMTURA CORPORATION (US) | 2011-11-01 | — | — | US | disclosed |
| WO-2011014529-A2 | HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS | CHEMTURA CORPORATION (US) | 2011-02-03 | — | — | WO | disclosed |
| US-20110028619-A1 | Hydrolytically stable phosphite compositions | SI GROUP, INC. | 2011-02-03 | — | — | US | disclosed |