Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922508 | 0.85 | PDE7A (0.55) | PDE7AIDO1TDP1PDE7BERN1 | |
| SCHEMBL4748682 | 0.85 | PDE7A (0.64) | PDE7AALDH1A1TDP1PDE7BERN1 | |
| SCHEMBL10924255 | 0.83 | PDE7A (0.76) | PDE7AIDO1ALDH1A1TDP1PDE7B | |
| SCHEMBL6927189 | 0.83 | MAPT (0.53) | PDE7ATDP1PDE7BERN1PDE4B | |
| SCHEMBL6925412 | 0.81 | PDE7A (0.52) | PDE7AIDO1TDP1PDE7BERN1 | |
| SCHEMBL6926885 | 0.80 | PDE7A (0.48) | PDE7AALDH1A1TDP1PDE7BERN1 | |
| SCHEMBL6927470 | 0.79 | PDE7A (0.50) | PDE7AALDH1A1TDP1PDE7BERN1 | |
| SCHEMBL6927026 | 0.78 | PDE7A (0.59) | PDE7AALDH1A1TDP1PDE7BERN1 | |
| SCHEMBL6925522 | 0.77 | GAA (0.53) | PDE7AALDH1A1TDP1PDE7BERN1 | |
| SCHEMBL10923911 | 0.77 | ALDH1A1 (0.58) | PDE7AIDO1ALDH1A1TDP1PDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| CN-1321153-A | telomerase inhibitors and methods of use thereof | GERON CORP (US) | 2001-11-07 | — | — | CN | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |