SCHEMBL692980

SCHEMBL692980

CSCC[C@H](N)C(=O)OC[C@H](N)C(=O)O.C[C@H](N)C(=O)OC(=O)[C@@H](N)[C@@H](C)OC(=O)CN

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 1/20 0.31
BHMT2 Q9H2M3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3995868 0.84 BHMT (0.35) BHMTBHMT2
Alanine SCHEMBL5582473 0.83 BHMT (0.33) BHMTBHMT2
Alanine SCHEMBL1409244 0.82 BHMT (0.32) BHMTBHMT2
Glycine SCHEMBL6361607 0.82 BHMT (0.36) BHMTBHMT2
SCHEMBL2551500 0.81 BHMT (0.38) BHMTBHMT2
SCHEMBL3995873 0.80 METAP2 (0.32)
Glycine SCHEMBL4005389 0.78 BHMT (0.40) BHMTBHMT2
SCHEMBL2260606 0.78 RNPEP (0.44) BHMTBHMT2
SCHEMBL5073184 0.78
SCHEMBL9755602 0.76 BHMT (0.34) BHMTBHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11761005-B2 Translocation and mutant ROS kinase in human non-small cell lung carcinoma CELL SIGNALING TECHNOLOGY, INC. (US) 2023-09-19 US disclosed
US-11505833-B2 Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer CELL SIGNALING TECHNOLOGY, INC. (US) 2022-11-22 US disclosed
EP-3336181-B1 EGFR AND ROS1 IN CANCER CELL SIGNALING TECHNOLOGY INC (US) 2022-01-12 EP disclosed
EP-3936621-A1 TRANSLOCATION AND MUTANT ROS KINASE IN HUMAN NON-SMALL CELL LUNG CARCINOMA Cell Signaling Technology, Inc. (US) 2022-01-12 EP disclosed
US-20210371933-A1 COMPOSITIONS FOR DETECTING MUTANT ANAPLASTIC LYMPHOMA KINASE IN LUNG CANCER CELL SIGNALING TECHNOLOGY, INC. (US) 2021-12-02 US disclosed
US-20210349095-A1 ROS KINASE IN LUNG CANCER CELL SIGNALING TECHNOLOGY, INC. (US) 2021-11-11 US disclosed
EP-3906921-A1 METHOD OF TREATING LUNG ADENOCARCINOMA Exelixis, Inc. (US) 2021-11-10 EP disclosed
US-10955416-B2 Compositions for detecting mutant anaplastic lymphoma kinase in human lung cancer CELL SIGNALING TECHNOLOGY, INC. (US) 2021-03-23 US disclosed
EP-3134084-B1 METHOD OF TREATING LUNG ADENOCARCINOMA EXELIXIS INC (US) 2021-03-17 EP disclosed
US-20210062196-A1 TRANSLOCATION AND MUTANT ROS KINASE IN HUMAN NON-SMALL CELL LUNG CARCINOMA CELL SIGNALING TECHNOLOGY, INC. (US) 2021-03-04 US disclosed
WO-2002077155-A2 KERATINOCYTE GROWTH FACTOR-2 HUMAN GENOME SCIENCES, INC. (US) 2002-10-03 WO disclosed
EP-1196441-A1 KERATINOCYTE GROWTH FACTOR-2 Human Genome Sciences, Inc. (US) 2002-04-17 EP disclosed
WO-2001002433-A1 KERATINOCYTE GROWTH FACTOR-2 HUMAN GENOME SCIENCES, INC. (US) 2001-01-11 WO disclosed
EP-1054900-A1 THERAPEUTIC USES OF KERATINOCYTE GROWTH FACTOR-2 Human Genome Sciences, Inc. (US) 2000-11-29 EP disclosed
EP-1041996-A1 KERATINOCYTE GROWTH FACTOR-2 FORMULATIONS Human Genome Sciences, Inc. (US) 2000-10-11 EP disclosed
EP-0948515-A1 HUMAN B-CELL TRANSLOCATION GENES-2 AND 3 HUMAN GENOME SCIENCES, INC. (US) 1999-10-13 EP disclosed
WO-1999041282-A1 THERAPEUTIC USES OF KERATINOCYTE GROWTH FACTOR-2 HUMAN GENOME SCIENCES, INC. (US) 1999-08-19 WO disclosed
WO-1999032135-A1 KERATINOCYTE GROWTH FACTOR-2 FORMULATIONS HUMAN GENOME SCIENCES, INC. (US) 1999-07-01 WO disclosed
WO-1998012204-A9 HUMAN B-CELL TRANSLOCATION GENES-2 AND 3 1998-08-27 WO disclosed
WO-1998012204-A1 HUMAN B-CELL TRANSLOCATION GENES-2 AND 3 HUMAN GENOME SCIENCES, INC. (US) 1998-03-26 WO disclosed