Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154712 | 0.84 | ELANE (0.46) | ALDH1A1ALOX15ELANECTSDKDM4E | |
| SCHEMBL2110850 | 0.84 | KDM4E (0.53) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL10982630 | 0.83 | ALDH1A1 (0.37) | ALDH1A1ALOX15ELANECTSDKDM4E | |
| SCHEMBL249223 | 0.82 | KCNK3 (0.49) | ALDH1A1ALOX15KCNK3KCNK9 | |
| SCHEMBL10749870 | 0.82 | ALDH1A1 (0.44) | ALDH1A1ALOX15ELANECTSDKDM4E | |
| SCHEMBL3357655 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ALOX15ELANECTSDKDM4E | |
| SCHEMBL2366561 | 0.78 | ALDH1A1 (0.44) | ALDH1A1ALOX15KDM4ETSHRTDP1 | |
| SCHEMBL2562387 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX15ELANECTSDKDM4E | |
| SCHEMBL16669782 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ALOX15ELANECTSDKDM4E | |
| SCHEMBL18281342 | 0.75 | KCNK3 (0.44) | ALDH1A1ALOX15KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051655-A4 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | ISTA PHARMACEUTICALS INC (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1051655-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | Ista Pharmaceuticals, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999039238-A1 | METHODS AND APPARATUS FOR ACCELERATED ORTHOKERATOLOGY | KERATOFORM, INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| US-4950813-A | Preparation of substituted benzotrichlorides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-21 | — | — | US | disclosed |
| US-4590016-A | Preparation of fluoromethylthiobenzoyl fluorides | BASF AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |