Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249223 | 0.84 | KCNK3 (0.49) | ALDH1A1ALOX15KCNK3KCNK9CYP11B1 | |
| SCHEMBL2366561 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ALOX15KCNK3KCNK9KDM4E | |
| SCHEMBL10749870 | 0.79 | ALDH1A1 (0.44) | ALDH1A1ALOX15KCNK3KCNK9KDM4E | |
| SCHEMBL23519085 | 0.79 | CXCL8 (0.44) | ALDH1A1NOTUMHPGDMAPTHTT | |
| SCHEMBL6930065 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX15KCNK3KCNK9KDM4E | |
| SCHEMBL23519089 | 0.78 | CXCL8 (0.46) | ALDH1A1NOTUMKDM4EHSD17B10HPGD | |
| SCHEMBL2154712 | 0.78 | ELANE (0.46) | ALDH1A1ALOX15KCNK3KCNK9KDM4E | |
| SCHEMBL18281342 | 0.77 | KCNK3 (0.44) | ALDH1A1ALOX15KCNK3KCNK9CYP11B1 | |
| SCHEMBL24361903 | 0.77 | NOTUM (0.43) | ALDH1A1ALOX15NOTUMKDM4EHSD17B10 | |
| SCHEMBL24361891 | 0.76 | NPSR1 (0.43) | ALDH1A1NOTUMKDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |