Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488738 | 0.85 | PPARA (0.48) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL931460 | 0.85 | PPARA (0.48) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24252852 | 0.79 | L3MBTL1 (0.48) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30467628 | 0.79 | L3MBTL1 (0.48) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29139681 | 0.78 | MAPT (0.49) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21218766 | 0.78 | TDP1 (0.32) | L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL29219604 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2NPC1MAPTRAB9ATDP1 | |
| SCHEMBL30467695 | 0.73 | L3MBTL1 (0.46) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24252446 | 0.73 | L3MBTL1 (0.46) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6926133 | 0.73 | HTR2A (0.49) | PPARAL3MBTL1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-1363624-A2 | FLUORO OXINDOLE DERIVATIVES AS MODULATORS OF KCNQ POTASSIUM CHANNELS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002066426-A2 | FLUORO OXINDOLE DERIVATIVES AS MODULATORS OF KCNQ POTASSIUM CHANNELS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-29 | — | — | WO | disclosed |