Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535668 | 0.97 | TSHR (0.53) | TSHRCYP1A2LMNACYP2A6CES2 | |
| SCHEMBL92023 | 0.97 | TSHR (0.53) | TSHRCYP1A2LMNACYP2A6CES2 | |
| Bromide SCHEMBL3129122 | 0.95 | TSHR (0.50) | TSHRCYP1A2LMNACYP2A6CES2 | |
| Bromide SCHEMBL3139794 | 0.95 | TSHR (0.50) | TSHRCYP1A2LMNACYP2A6CES2 | |
| Perchlorate SCHEMBL3132374 | 0.88 | TSHR (0.43) | TSHRCYP1A2LMNACYP2A6CES2 | |
| SCHEMBL3141304 | 0.88 | CYP1A2 (0.48) | TSHRCYP1A2LMNACYP2A6CES2 | |
| Perchlorate SCHEMBL3136664 | 0.88 | TSHR (0.43) | TSHRCYP1A2LMNACYP2A6CES2 | |
| SCHEMBL31501941 | 0.88 | TSHR (0.43) | TSHRCYP1A2LMNACYP2A6CES2 | |
| SCHEMBL30118167 | 0.88 | TSHR (0.43) | TSHRCYP1A2LMNACYP2A6CES2 | |
| SCHEMBL3143548 | 0.88 | CYP1A2 (0.48) | TSHRCYP1A2LMNACYP2A6CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1158363-B1 | Positive resist composition and onium salts of saccharin derivatives | FUJIFILM CORP (JP) | 2014-01-22 | — | — | EP | disclosed |
| EP-1160095-B1 | Heat-sensitive composition and planographic printing plate precursor | FUJIFILM CORP (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-6660446-B2 | Generating acid upon heating | FUJI PHOTO FILM CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-6605409-B2 | Includes a compound that generates a specific sulfonimide compound by irradiation with an actinic ray or a radiation and (B) a resin having an acid decomposable group which increases solubility in an alkali developer; improved resolving power | FUJI PHOTO FILM CO., LTD. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020025489-A1 | Generating acid upon heating | FUJIFILM CORPORATION (JP) | 2002-02-28 | — | — | US | disclosed |
| US-20020006578-A1 | Positive resist composition | FUJI PHOTO FILM CO., LTD. | 2002-01-17 | — | — | US | disclosed |
| EP-1160095-A2 | Heat-sensitive composition and planographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2001-12-05 | — | — | EP | disclosed |
| EP-1158363-A1 | Positive resist composition and onium salts of saccharin derivatives | FUJI PHOTO FILM CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |