Perchlorate

Perchlorate

SCHEMBL3136664

Clc1ccc([S+](c2ccccc2)c2ccccc2)cc1.[O-][Cl+3]([O-])([O-])[O-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
CYP1A2 P05177 1/20 0.42
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
G6PD P11413 1/20 0.38
NPC1 O15118 1/20 0.38
PTGS2 P35354 2/20 0.37
PTGS1 P23219 1/20 0.37
LMNA P02545 2/20 0.36
CYP2A6 P11509 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35
TRPV6 Q9H1D0 1/20 0.35
IDO1 P14902 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perchlorate SCHEMBL3132374 1.00 TSHR (0.43) TSHRCYP1A2KDM4EALDH1A1POLB
SCHEMBL1535668 0.91 TSHR (0.53) TSHRCYP1A2KDM4EG6PDLMNA
SCHEMBL92023 0.91 TSHR (0.53) TSHRCYP1A2KDM4EG6PDLMNA
Bromide SCHEMBL3129122 0.88 TSHR (0.50) TSHRCYP1A2KDM4EG6PDLMNA
Bromide SCHEMBL3139794 0.88 TSHR (0.50) TSHRCYP1A2KDM4EG6PDLMNA
Iodide SCHEMBL6930682 0.88 TSHR (0.50) TSHRCYP1A2KDM4EG6PDLMNA
Perchlorate SCHEMBL108183 0.85 CYP3A4 (0.33) TSHRKDM4EALDH1A1HTTNPC1
SCHEMBL31501941 0.82 TSHR (0.43) TSHRCYP1A2KDM4EG6PDLMNA
SCHEMBL30118167 0.82 TSHR (0.43) TSHRCYP1A2KDM4EG6PDLMNA
SCHEMBL3141304 0.82 CYP1A2 (0.48) TSHRCYP1A2KDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2007-04-12 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070083060-A1 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid ARSA, HAO2, HAO1 TSHR 1087/4885CYP1A2 378/4885KDM4E 2848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.