Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 4/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | LHCGR | P22888 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427027 | 0.86 | BRAF (0.51) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4432076 | 0.86 | LHCGR (0.50) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4419271 | 0.86 | LHCGR (0.53) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6216817 | 0.77 | ALDH1A1 (0.48) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6217543 | 0.76 | SMN1; SMN2 (0.44) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4331233 | 0.76 | LHCGR (0.77) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6216364 | 0.76 | ABCG2 (0.45) | CHRM4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5025998 | 0.76 | BRAF (0.46) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6217503 | 0.76 | BRAF (0.42) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6216809 | 0.74 | MAPT (0.43) | BRAFPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569863-B1 | Luteinizing hormone (LH) agonists for controlling fertility | AKZO NOBEL NV (NL) | 2003-05-27 | — | — | US | disclosed |