Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RGS4 | P49798 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RGS8 | P57771 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933855 | 0.90 | ALDH1A1 (0.46) | ALDH1A1GAATHRBMEN1KMT2A | |
| SCHEMBL6936647 | 0.86 | PDE4A (0.50) | ALDH1A1GAAHPGDCYP3A4CYP2C19 | |
| SCHEMBL6934220 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAATHRBMEN1KMT2A | |
| SCHEMBL6936624 | 0.78 | PDE4A (0.53) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL6930285 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL8489121 | 0.74 | APP (0.43) | ALDH1A1GAAMEN1KMT2ACYP3A4 | |
| SCHEMBL6935775 | 0.74 | CFTR (0.48) | ALDH1A1GAAMEN1KMT2AHPGD | |
| SCHEMBL6933471 | 0.73 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6936525 | 0.72 | GAA (0.39) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL6733056 | 0.70 | RGS4 (0.49) | ALDH1A1GAATHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | claimed |
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-5958382-A | ARTIFICIAL TANNING AND/OR COLORING OF HUMAN SKIN AND/OR HAIR | SOCIETE L'OREAL S.A. (FR) | 1999-09-28 | — | — | US | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |