SCHEMBL6931355

SCHEMBL6931355

C#CC(O)CCCCC.C#CC(O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.41
CSNK1E P49674 1/20 0.40
NAAA Q02083 2/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.38
ASAH1 Q13510 2/20 0.38
OPRM1 P35372 2/20 0.37
OPRD1 P41143 2/20 0.37
OPRK1 P41145 2/20 0.37
OPRL1 P41146 2/20 0.37
ACER2 Q5QJU3 1/20 0.37
POLB P06746 1/20 0.36
CNR2 P34972 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31682124 0.81 CSNK1E (0.45) AOC3CSNK1ENAAAALDH1A1KDM4E
SCHEMBL6931356 0.79 CACNA2D1 (0.50) AOC3CSNK1ENAAAALDH1A1KDM4E
SCHEMBL766022 0.79
SCHEMBL235985 0.79
SCHEMBL134483 0.79
SCHEMBL15283559 0.77 GPR84 (0.45) KDM4ELMNAPOLBCYP1A2CYP3A4
SCHEMBL6285996 0.77 GPR84 (0.45) KDM4ELMNAPOLBCYP1A2CYP3A4
SCHEMBL12994143 0.77 GPR84 (0.45) KDM4ELMNAPOLBCYP1A2CYP3A4
SCHEMBL9793919 0.77 GPR84 (0.45) KDM4ELMNAPOLBCYP1A2CYP3A4
SCHEMBL1888013 0.77 GPR84 (0.45) KDM4ELMNAPOLBCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660072-B2 An acetylenic alcohol stabilizer for corrosion resistance HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2003-12-09 US disclosed