Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15650691 | 0.98 | HTT (0.36) | HTTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL5949408 | 0.84 | LMNA (0.37) | HTTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL1633598 | 0.84 | S1PR2 (0.34) | ALDH1A1KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL4501039 | 0.82 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL29560985 | 0.82 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL6629648 | 0.81 | LMNA (0.36) | HTTLMNAALDH1A1MAPK1KDM4E | |
| SCHEMBL9608992 | 0.80 | NPC1 (0.39) | HTTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL23287933 | 0.79 | HTT (0.35) | HTTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL29714427 | 0.78 | LOX (0.45) | HTTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL19755849 | 0.78 | LOX (0.45) | HTTSMN1; SMN2LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622713-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | Lhotse Bio, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112895-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LHOTSE BIO, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112895-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LHOTSE BIO, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2011012622-A1 | BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF GLYTL MEDIATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2011-02-03 | — | — | WO | disclosed |