Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.67 |
| ▸ | DRD3 | P35462 | 13/20 | 0.67 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | FYN | P06241 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411424 | 0.94 | DRD2 (0.70) | DRD2DRD3HTR1AFYNDRD4 | |
| SCHEMBL7411429 | 0.94 | DRD2 (0.70) | DRD2DRD3HTR1AFYNDRD4 | |
| SCHEMBL8689650 | 0.88 | DRD3 (0.64) | DRD2DRD3HTR1AFYNDRD4 | |
| SCHEMBL7854718 | 0.88 | DRD3 (0.64) | DRD2DRD3HTR1AFYNDRD4 | |
| SCHEMBL7854684 | 0.88 | DRD3 (0.64) | DRD2DRD3HTR1AFYNDRD4 | |
| SCHEMBL8339894 | 0.87 | DRD2 (0.65) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL8339900 | 0.87 | DRD2 (0.65) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL7298755 | 0.87 | DRD2 (0.65) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL6561256 | 0.82 | DRD2 (0.67) | DRD2DRD3HTR1AFYNDRD4 | |
| SCHEMBL7499793 | 0.82 | DRD2 (0.89) | DRD2DRD3HTR1AFYNDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768307-B1 | Heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-11-26 | — | — | EP | disclosed |
| US-5726208-A | Heterocyclic tertiary amines | ADIR ET COMPAGNIE (FR) | 1998-03-10 | — | — | US | disclosed |
| EP-0768307-A1 | Heterocyclic tertiary amines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-04-16 | — | — | EP | disclosed |