Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877495 | 1.00 | NR3C2 (0.67) | NR3C2KDM4ECACNA1CALDH1A1CYP1A2 | |
| SCHEMBL9644465 | 0.93 | NR3C2 (0.77) | NR3C2KDM4ECACNA1CCYP1A2CYP3A4 | |
| SCHEMBL8923705 | 0.89 | NR3C2 (0.52) | NR3C2KDM4ECACNA1CALDH1A1NPSR1 | |
| SCHEMBL7162892 | 0.89 | NR3C2 (0.52) | NR3C2KDM4ECACNA1CALDH1A1NPSR1 | |
| SCHEMBL7275395 | 0.88 | NR3C2 (0.55) | NR3C2KDM4ECACNA1CALDH1A1MET | |
| SCHEMBL9123412 | 0.87 | NR3C2 (0.54) | NR3C2CACNA1C | |
| SCHEMBL9644691 | 0.86 | NR3C2 (0.73) | NR3C2KDM4ECACNA1CALDH1A1CYP1A2 | |
| SCHEMBL9155066 | 0.84 | NR3C2 (0.63) | NR3C2KDM4ECACNA1CALDH1A1CYP1A2 | |
| SCHEMBL9467948 | 0.83 | NR3C2 (0.62) | NR3C2KDM4ECACNA1CALDH1A1CYP1A2 | |
| SCHEMBL9096711 | 0.83 | NR3C2 (0.51) | NR3C2KDM4ECACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875078-A1 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | Dompe' Farmaceutici S.P.A. (IT) | 2021-09-08 | — | — | EP | claimed |
| EP-3875078-A1 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | Dompe' Farmaceutici S.P.A. (IT) | 2021-09-08 | — | — | EP | disclosed |
| EP-1045709-B1 | METHOD AND DEVICE FOR IN-SITU FORMULATION OF A MEDICINAL SOLUTION FOR PARENTERAL APPLICATION | BAYER AG (DE) | 2003-12-03 | — | — | EP | disclosed |
| EP-1045709-A1 | METHOD AND DEVICE FOR IN-SITU FORMULATION OF A MEDICINAL SOLUTION FOR PARENTERAL APPLICATION | Bayer Aktiengesellschaft (DE) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999032175-A1 | METHOD AND DEVICE FOR IN-SITU FORMULATION OF A MEDICINAL SOLUTION FOR PARENTERAL APPLICATION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-01 | — | — | WO | disclosed |