Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.52 |
| ▸ | HTR1A | P08908 | 8/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575709 | 0.89 | DRD2 (0.44) | KCNH2HTR1ASIGMAR1DRD2HTR2A | |
| SCHEMBL4576039 | 0.81 | DRD2 (0.45) | KCNH2HTR1ASIGMAR1DRD2HTR2A | |
| SCHEMBL27581509 | 0.79 | DRD2 (0.65) | KCNH2HTR1ASIGMAR1DRD2DRD3 | |
| SCHEMBL9255868 | 0.78 | DRD3 (0.68) | KCNH2HTR1ASIGMAR1DRD2HTR2A | |
| SCHEMBL29314713 | 0.77 | SIGMAR1 (0.71) | KCNH2HTR1ASIGMAR1DRD2HTR2A | |
| SCHEMBL29005764 | 0.76 | KCNH2 (0.45) | KCNH2HTR1ASIGMAR1DRD2DRD3 | |
| SCHEMBL4222683 | 0.75 | CHRNA7 (0.62) | KCNH2SIGMAR1DRD2 | |
| SCHEMBL6135422 | 0.75 | SLC6A2 (0.60) | KCNH2HTR1ASIGMAR1DRD2HTR2A | |
| SCHEMBL6135382 | 0.75 | HRH3 (0.57) | KCNH2DRD2HRH1DRD3HTR7 | |
| SCHEMBL6135083 | 0.75 | HRH3 (0.57) | KCNH2DRD2HRH1DRD3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366066-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002072621-A2 | CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-19 | — | — | WO | disclosed |