Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.56 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | PLAT | P00750 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544213 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTNPC1HSP90AA1 | |
| SCHEMBL30783842 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTNPC1HSP90AA1 | |
| SCHEMBL6930600 | 0.72 | F2 (1.00) | F2F10PLATPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6929471 | 0.71 | F2 (0.98) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL13425980 | 0.69 | PDE10A (0.45) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL1918235 | 0.69 | PDE10A (0.45) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL3040780 | 0.69 | PDE10A (0.45) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL7111564 | 0.66 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL7475300 | 0.66 | PKN1 (0.49) | ALDH1A1LMNAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL15372172 | 0.65 | MAPT (0.46) | ALDH1A1MAPTRAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225131-A1 | Thrombin inhibitors | BURGEY CHRISTOPHER S (US) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225131-A1 | Thrombin inhibitors | TFPI, SERPINC1, PLAT | F2 5/4885F10 27/4885PLAT 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.