SCHEMBL6932147

SCHEMBL6932147

CCOC(=O)CN(CC(=O)OCC)c1ccc([Te]c2ccc(N(CC(=O)OCC)CC(=O)OCC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.43
AR P10275 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
GLA P06280 1/20 0.38
THRB P10828 1/20 0.38
CASP1 P29466 1/20 0.38
HTT P42858 1/20 0.38
CASP7 P55210 1/20 0.38
ATM Q13315 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5988525 0.81 MAPT (0.49) PPARGARALDH1A1MAPTKDM4E
SCHEMBL8624227 0.81 SMN1; SMN2 (0.57) PPARGSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL17845859 0.80 ALDH1A1 (0.59) PPARGARSMN1; SMN2CA12CA1
SCHEMBL15004697 0.80 PPARG (0.62) PPARGSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL28300064 0.78 MAPT (0.48) PPARGSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL9512868 0.78 HCRTR2 (0.48) PPARGSMN1; SMN2CA12CA1CA2
SCHEMBL4517708 0.77 SMN1; SMN2 (0.53) PPARGSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL14156361 0.76 SMN1; SMN2 (0.47) PPARGARSMN1; SMN2CA12CA1
SCHEMBL14508465 0.75 SMN1; SMN2 (0.51) PPARGSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL20813057 0.75 MAPT (0.47) PPARGARALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747704-B1 Immunoassay element containing a diaryl telluride compound to increase its stability ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-12-10 EP disclosed
EP-0903583-B1 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-11-12 EP disclosed
US-5928886-A SUPPORT HAVING ZONE OF ENZYME LABELED LIGAND OR ENZYME LABELED RECEPTOR, SPREADING ZONE, ZONE OF IMMOBILIZED RECEPTOR OF LIGAND, AND GRAVURE ZONE WITH DIARYL TELLURIDE; INCREASED STORAGE STABILITY JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1999-07-27 US disclosed
EP-0903583-A2 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements Ortho-Clinical Diagnostics, Inc. (US) 1999-03-24 EP disclosed
US-5686254-A Reduction in first slide bias and improved enzyme stability by the incorporation of diaryl tellurides in thin-film immunoassay elements JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1997-11-11 US disclosed
EP-0747704-A2 Immunoassay element containing a diaryl telluride compound to increase its stability Johnson & Johnson Clinical Diagnostics, Inc. (US) 1996-12-11 EP disclosed