Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419872 | 0.93 | FFAR1 (0.77) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL6935065 | 0.86 | GPBAR1 (0.85) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL6934343 | 0.85 | GPBAR1 (0.59) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL7807149 | 0.84 | FFAR1 (0.68) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9022221 | 0.84 | CYSLTR1 (0.67) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL6089121 | 0.82 | CYSLTR1 (0.69) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL13772730 | 0.82 | GPBAR1 (0.70) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL8902567 | 0.82 | ALOX5 (0.72) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL1419915 | 0.82 | ALOX5 (0.72) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9828714 | 0.81 | FFAR1 (0.67) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086079-B1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA A S (CZ) | 2003-05-07 | — | — | EP | disclosed |
| US-6303612-B1 | USED AS ANTIINFLAMMATORY AND/OR ANTIASTHMATIC AGENTS | LECIVA, A.S. (CZ) | 2001-10-16 | — | — | US | disclosed |
| EP-1086079-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | Leciva, A.S. (CZ) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999067208-A1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA, A.S. (CZ) | 1999-12-29 | — | — | WO | disclosed |