Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | ST6GAL1 | P15907 | 5/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060610 | 0.90 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL236108 | 0.90 | LMNA (0.69) | LMNATHRBMTORMDM2NCOA1 | |
| Hydrochloric Acid SCHEMBL11852751 | 0.89 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10887181 | 0.88 | LMNA (0.48) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10887173 | 0.88 | LMNA (0.48) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL5824295 | 0.87 | LMNA (0.56) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL2031869 | 0.86 | LMNA (0.55) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL12724455 | 0.86 | LMNA (0.60) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11807658 | 0.85 | LMNA (0.48) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10589686 | 0.85 | LMNA (0.48) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363927-A2 | METHOD FOR THE SYNTHESIS OF 2',3'-DIDEOXY-2',3'-DIDEHYDRONUCLEOSIDES | Pharmasset Limited (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070533-A2 | METHOD FOR THE SYNTHESIS OF 2',3'-DIDEOXY-2',3'-DIDEHYDRONUCLEOSIDES | PHARMASSET LTD. (BB) | 2002-09-12 | — | — | WO | disclosed |