SCHEMBL236108

SCHEMBL236108

CC(=O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.69
THRB P10828 1/20 0.69
MTOR P42345 1/20 0.69
MDM2 Q00987 1/20 0.69
NCOA1 Q15788 1/20 0.69
NCOA3 Q9Y6Q9 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.60
TSHR P16473 1/20 0.59
GLA P06280 1/20 0.59
P2RY2 P41231 1/20 0.56
ST6GAL1 P15907 6/20 0.54
NT5E P21589 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060610 1.00 LMNA (0.69) LMNATHRBMTORMDM2NCOA1
Hydrochloric Acid SCHEMBL11852751 0.99 LMNA (0.67) LMNATHRBMTORMDM2NCOA1
SCHEMBL12724455 0.91 LMNA (0.60) LMNATHRBMTORMDM2NCOA1
SCHEMBL5824295 0.90 LMNA (0.56) LMNATHRBMTORMDM2NCOA1
SCHEMBL6932191 0.90 LMNA (0.56) LMNATHRBMTORMDM2NCOA1
SCHEMBL331768 0.90 LMNA (0.70) LMNATHRBMTORMDM2NCOA1
SCHEMBL30608768 0.90 LMNA (0.74) LMNATHRBMTORMDM2NCOA1
SCHEMBL25382718 0.89 LMNA (0.64) LMNATHRBMTORMDM2NCOA1
SCHEMBL2031869 0.89 LMNA (0.55) LMNATHRBMTORMDM2NCOA1
SCHEMBL28322026 0.89 LMNA (0.64) LMNATHRBMTORMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038850-A1 LIPID NANOPARTICLES AND METHODS FOR SENSITIZING RESPONSE TO AN IMMUNOTHERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 WO claimed
EP-4384635-A1 IN SITU EPITRANSCRIPTOMIC PROFILING The Broad Institute Inc. (US) 2024-06-19 EP claimed
WO-2024123812-A1 FUSION PROTEINS FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES SHATTUCK LABS, INC. (US) 2024-06-13 WO claimed
CN-117886868-A Preparation method of 5' -DMT nucleoside compound 天津奥瑞芙生物医药有限公司 2024-04-16 CN claimed
CN-116964220-A Multiplex analysis of RNA and DNA modifications 阿丽达生物科学公司 2023-10-27 CN claimed
EP-4251760-A1 MULTIPLEXED PROFILING OF RNA AND DNA MODIFICATIONS Alida Biosciences, Inc. (US) 2023-10-04 EP claimed
US-11773425-B2 Multiplexed profiling of RNA and DNA modifications Alida Biosciences Inc. (US) 2023-10-03 US claimed
WO-2022115608-A9 MULTIPLEXED PROFILING OF RNA AND DNA MODIFICATIONS ALIDA BIOSCIENCES, INC. (US) 2023-06-15 WO claimed
WO-2023018756-A1 IN SITU EPITRANSCRIPTOMIC PROFILING THE BROAD INSTITUTE, INC. (US) 2023-02-16 WO claimed
WO-2022140380-A1 METABOLOMIC SIGNATURES FOR PREDICTING, DIAGNOSING, AND PROGNOSING CHRONIC PANCREATITIS PANCREOMICS LLC (US) 2022-06-30 WO claimed
US-20120116067-A1 METHOD FOR THE SOLID PHASE-BASED PRODUCTION OF PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES UNIVERSITAET HAMBURG (DE) 2012-05-10 US claimed
EP-2427470-A1 METHOD FOR THE SOLID PHASE-BASED PRODUCTION OF PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES Universität Hamburg (DE) 2012-03-14 EP claimed
WO-2011113607-A1 MOLECULARLY IMPRINTED POLYMERS FOR ELIMINATING METABOLITES FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) 2011-09-22 WO claimed
US-20110137023-A1 METHOD FOR PRODUCING PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES UNIVERSITAET HAMBURG (DE) 2011-06-09 US claimed
EP-2321330-A1 METHOD FOR PRODUCING PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES Universität Hamburg (DE) 2011-05-18 EP claimed
US-20110028705-A1 METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS UNIVERSITAET HAMBURG (DE) 2011-02-03 US claimed
EP-2262820-A1 METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS Universität Hamburg (DE) 2010-12-22 EP claimed
WO-2010127666-A1 METHOD FOR THE SOLID PHASE-BASED PRODUCTION OF PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES UNIVERSITÄT HAMBURG (DE) 2010-11-11 WO claimed
WO-2010015245-A1 METHOD FOR PRODUCING PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES UNIVERSITÄT HAMBURG (DE) 2010-02-11 WO claimed
WO-2009121347-A1 METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS UNIVERSITÄT HAMBURG (DE) 2009-10-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110137023-A1 METHOD FOR PRODUCING PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES TYMP, PNP, NUDT1 LMNA 3246/4885THRB 4815/4885MTOR 1502/4885
US-20110028705-A1 METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS MTAP, PHOSPHO1, PNKP LMNA 3041/4885THRB 1384/4885MTOR 1144/4885
US-20120116067-A1 METHOD FOR THE SOLID PHASE-BASED PRODUCTION OF PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES PNP, TYMP, DPYD LMNA 2594/4885THRB 4656/4885MTOR 1133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.