Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SOD1 | P00441 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472525 | 0.90 | MAOB (0.55) | MAOBALDH1A1KDM4EMRGPRX4HPGD | |
| SCHEMBL31573499 | 0.90 | MAOB (0.55) | MAOBALDH1A1KDM4EMRGPRX4HPGD | |
| Formaldehyde SCHEMBL27685853 | 0.87 | MAOB (0.51) | MAOBALDH1A1KDM4EMRGPRX4SOD1 | |
| 3-(Allyloxy)Phenol SCHEMBL483058 | 0.87 | APP (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| 3-(Allyloxy)Phenol SCHEMBL27721429 | 0.85 | APP (0.49) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL7365149 | 0.83 | MAOB (0.39) | MAOBALDH1A1KDM4EHPGDLMNA | |
| 3-(Allyloxy)Phenol SCHEMBL27494286 | 0.83 | APP (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| 3-(Allyloxy)Phenol SCHEMBL27650695 | 0.82 | DRD2 (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| 3-(Allyloxy)Phenol SCHEMBL6690965 | 0.82 | CHRNB2 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| 3-(Allyloxy)Phenol SCHEMBL27494285 | 0.79 | KAT6A (0.47) | ALDH1A1KDM4EHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363876-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | Abbott Laboratories (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002064550-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2002-08-22 | — | — | WO | disclosed |