Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314423 | 0.91 | HIF1A (0.43) | HIF1ACYP2C9CYP2C19HMGCRMEN1 | |
| SCHEMBL11167688 | 0.80 | KMT2A (0.41) | HIF1ACYP2C9CYP2C19HMGCRMEN1 | |
| SCHEMBL10570668 | 0.75 | ALDH1A1 (0.36) | HIF1ACYP2C9CYP2C19HMGCRMEN1 | |
| SCHEMBL10724436 | 0.74 | GAA (0.36) | HMGCRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL17881233 | 0.72 | ALDH1A1 (0.42) | HIF1ACYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL562628 | 0.71 | KMT2A (0.47) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL2671331 | 0.71 | HMGCR (0.53) | HIF1ACYP2C9CYP2C19HMGCRMEN1 | |
| SCHEMBL11205743 | 0.71 | HIF1A (0.45) | HIF1ACYP2C9CYP2C19HMGCRMEN1 | |
| SCHEMBL7506204 | 0.70 | GAA (0.34) | ALDH1A1GAAKDM4E | |
| SCHEMBL1263508 | 0.69 | HMGCR (0.35) | HMGCRMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818526-B1 | Stabilizers for the prevention of gum formation in gasoline | CIBA SC HOLDING AG (CH) | 2003-02-12 | — | — | EP | claimed |