SCHEMBL314423

SCHEMBL314423

CN1C(C)(C)CC(C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)O)CC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HMGCR P04035 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 7/20 0.39
KDM4E B2RXH2 4/20 0.39
MAPT P10636 3/20 0.39
GAA P10253 5/20 0.37
TSHR P16473 3/20 0.37
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.37
THRB P10828 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CACNA1A O00555 1/20 0.36
CACNA2D1 P54289 1/20 0.36
CACNB1 Q02641 1/20 0.36
MAOB P27338 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932275 0.91 HIF1A (0.43) HIF1ACYP2C9CYP2C19HMGCRMEN1
SCHEMBL11167688 0.82 KMT2A (0.41) HIF1ACYP2C9CYP2C19HMGCRMEN1
SCHEMBL3683968 0.79 HMGCR (0.41) HIF1ACYP2C9CYP2C19HMGCRMEN1
SCHEMBL1695282 0.78 HMGCR (0.36) HMGCRMEN1KMT2AALDH1A1KDM4E
SCHEMBL9626834 0.78 ALDH1A1 (0.39) HIF1ACYP2C9CYP2C19HMGCRMEN1
SCHEMBL1263508 0.78 HMGCR (0.35) HMGCRMEN1KMT2AALDH1A1KDM4E
SCHEMBL2687904 0.78 GAA (0.40) HIF1AHMGCRMEN1KMT2AALDH1A1
SCHEMBL697946 0.77 HMGCR (0.36) HIF1AHMGCRMEN1KMT2AALDH1A1
SCHEMBL2024345 0.77 CACNA1A (0.39) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL2949729 0.76 ALDH1A1 (0.39) HIF1ACYP2C9CYP2C19HMGCRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 EP disclosed
EP-2758462-B1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2018-03-07 EP disclosed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 US disclosed
US-9315760-B2 Ashless lubricant composition VANDERBILT CHEMICALS, LLC (US) 2016-04-19 US disclosed
US-20150087568-A1 ASHLESS LUBRICANT COMPOSITION VANDERBILT CHEMICALS, LLC 2015-03-26 US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 US disclosed
US-20140213493-A1 ASHLESS LUBRICANT COMPOSITION VANDERBILT CHEMICALS, LLC (US) 2014-07-31 US disclosed
EP-2594132-A1 Stabilisation of iodine containing compounds with polymers containing nitrogen Lanxess Deutschland GmbH (DE) 2013-05-22 EP disclosed
EP-2144980-B1 LUBRICANT ANTIOXIDANT COMPOSITIONS CONTAINING A METAL COMPOUND AND A HINDERED AMINE VANDERBILT CO R T (US) 2013-01-16 EP disclosed
EP-0083308-B1 PROCESS FOR STABILISING FUNGICIDES CIBA-GEIGY AG (CH) 1986-03-05 EP disclosed
US-4552885-A FOR LATEX PAINTS, TETRAALKYL PYRIDINES CIBA GEIGY CORPORATION (US) 1985-11-12 US disclosed
US-4511596-A 2,2,6,6-TETRAALKYLPIPERIDINE DERIVATIVES AS CURING PROMOTERS CIBA-GEIGY CORPORATION (US) 1985-04-16 US disclosed
US-4426471-A TETRAALKYLPIPERIDINES CIBA-GEIGY CORPORATION (US) 1984-01-17 US disclosed
US-4426472-A TETRAALKYLPIPERIDINES CIBA-GEIGY CORPORATION (US) 1984-01-17 US disclosed
EP-0016723-B1 LIGHT STABILISATION OF TWO-LAYER COMPOSITE LACQUERS CIBA-GEIGY AG (CH) 1983-06-01 EP disclosed
EP-0015230-B1 STABILIZED ORGANIC POLYMER COMPRISING 2-(2-HYDROXY-3,5-DI-TERT-OCTYLPHENYL)-2H-BENZOTRIAZOLE AS A LIGHT-STABILIZER CIBA-GEIGY AG (CH) 1983-02-23 EP disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M HIF1A 2250/4885CYP2C9 4489/4885CYP2C19 3756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.