SCHEMBL6932293

SCHEMBL6932293

COC(=O)C(=NOC(C)(C)C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SRC P12931 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ELANE P08246 1/20 0.38
CES1 P23141 3/20 0.38
CES2 O00748 2/20 0.37
TNF P01375 1/20 0.37
KLF5 Q13887 1/20 0.37
NOD1 Q9Y239 1/20 0.37
ACHE P22303 1/20 0.37
KCNN4 O15554 1/20 0.37
GAA P10253 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935492 0.85 TDP1 (0.46) TDP1ALDH1A1SMN1; SMN2MAPTCES1
SCHEMBL6935112 0.84 SMN1; SMN2 (0.43) TSHRTDP1ALDH1A1HSD17B10SRC
SCHEMBL6934141 0.84 CYP2D6 (0.43) TSHRTDP1ALDH1A1HSD17B10SRC
SCHEMBL6932532 0.83 HDAC8 (0.44) SMN1; SMN2CYP2C19RAB9APOLBKMT2A
SCHEMBL27446293 0.82 TSHR (0.50) TSHRTDP1SRCSMN1; SMN2CYP3A4
SCHEMBL7457347 0.82 TSHR (0.50) TSHRTDP1SRCSMN1; SMN2CYP3A4
SCHEMBL11455069 0.80 SMN1; SMN2 (0.36) TSHRALDH1A1SRCSMN1; SMN2CYP1A2
SCHEMBL11455068 0.80 SMN1; SMN2 (0.36) TSHRALDH1A1SRCSMN1; SMN2CYP1A2
SCHEMBL6932501 0.78 PKM (0.47) TDP1ALDH1A1SMN1; SMN2MAPTL3MBTL1
SCHEMBL6157370 0.77 GAA (0.57) TSHRTDP1ALDH1A1SRCSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1200393-B1 OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY MONSANTO TECHNOLOGY LLC (US) 2003-12-10 EP disclosed
EP-1200393-A1 OXIME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY Monsanto Technology LLC (US) 2002-05-02 EP disclosed
US-20020045655-A1 Oxime amides and hydrazone amides having fungicidal activity MONSANTO TECHNOLOGY LLC. 2002-04-18 US disclosed
US-6359156-B1 CONTROLLING DISEASES IN CEREAL PLANTS MONSANTO TECHNOLOGY LLC 2002-03-19 US disclosed
US-6297271-B1 CONTROLLING TAKE-ALL DISEASE IN A PLANT MONSANTO TECHNOLOGY LLC 2001-10-02 US disclosed
WO-2001012590-A1 OXYME AMIDES AND HYDRAZONE AMIDES HAVING FUNGICIDAL ACTIVITY MONSANTO TECHNOLOGY LLC (US) 2001-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045655-A1 Oxime amides and hydrazone amides having fungicidal activity AADAC, HAAO, OGA TSHR 2113/4885TDP1 2011/4885ALDH1A1 1260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.