Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457347 | 1.00 | TSHR (0.50) | TSHRHIF1ASMN1; SMN2SRCGAA | |
| SCHEMBL9196464 | 0.87 | PARP10 (0.49) | HIF1ASMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL8007984 | 0.84 | TSHR (0.48) | TSHRSMN1; SMN2SRCGAACYP2C19 | |
| SCHEMBL3958996 | 0.84 | TSHR (0.48) | TSHRSMN1; SMN2SRCGAACYP2C19 | |
| SCHEMBL3689392 | 0.84 | TSHR (0.48) | TSHRSMN1; SMN2SRCGAACYP2C19 | |
| SCHEMBL27447670 | 0.84 | ELANE (0.45) | TSHRHIF1AMAPTRAB9AL3MBTL1 | |
| SCHEMBL2045474 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2SRCGAACYP2C19 | |
| SCHEMBL2045476 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2SRCGAACYP2C19 | |
| SCHEMBL29172895 | 0.83 | TDP1 (0.52) | SMN1; SMN2GAAMAPTRAB9ACES1 | |
| SCHEMBL9659551 | 0.83 | CA1 (0.52) | HIF1AGAAMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104059027-B | One class contains (E)-methoxyimino methyl phenylacetate compounds of 1,2,4-triazole and its production and use | HEBEI UNIVERSITY (CN) | 2015-10-28 | — | — | CN | claimed |
| CN-104059027-A | (E)-methyl 2-methoxyiminobenzeneacetate compound containing 1, 2, 4-triazole and preparation method and application thereof | UNIV HEBEI | 2014-09-24 | — | — | CN | claimed |
| CN-103613542-A | Aryl pyrazole compound containing -methoxy imino methyl phenylacetate, preparation method and application | NANJING UNIVERSITY OF TECHNOLOGY | 2014-03-05 | — | — | CN | claimed |
| CN-104059027-B | One class contains (E)-methoxyimino methyl phenylacetate compounds of 1,2,4-triazole and its production and use | HEBEI UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-104059027-B | One class contains (E)-methoxyimino methyl phenylacetate compounds of 1,2,4-triazole and its production and use | HEBEI UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-104059027-A | (E)-methyl 2-methoxyiminobenzeneacetate compound containing 1, 2, 4-triazole and preparation method and application thereof | UNIV HEBEI | 2014-09-24 | — | — | CN | disclosed |
| CN-103613542-A | Aryl pyrazole compound containing -methoxy imino methyl phenylacetate, preparation method and application | NANJING UNIVERSITY OF TECHNOLOGY | 2014-03-05 | — | — | CN | disclosed |
| CN-1118349-A | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR SPA (IT) | 1996-03-13 | — | — | CN | disclosed |