SCHEMBL6932613

SCHEMBL6932613

Cc1cc(C(C)(C)c2ccc(Oc3cccc(N)c3)cc2)ccc1Oc1cccc(N)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
ALDH1A1 P00352 6/20 0.45
MAPT P10636 5/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
MITF O75030 1/20 0.44
GFER P55789 1/20 0.44
KMT2A Q03164 1/20 0.44
NLRP1 Q9C000 1/20 0.44
NOD2 Q9HC29 1/20 0.44
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
CYP3A4 P08684 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ATM Q13315 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933749 0.94 MAOB (0.47) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL9576142 0.90 ALDH1A1 (0.47) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL202158 0.88 MAOB (0.63) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL29374472 0.88 MAOB (0.63) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL125626 0.88 MAOB (0.63) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL30853973 0.88 MAOB (0.63) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL29492480 0.88 MAOB (0.63) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL1855632 0.87 ALDH1A1 (0.42) ALDH1A1MAPTSMN1; SMN2GAAMEN1
SCHEMBL29363720 0.87 ALDH1A1 (0.56) MAOBALDH1A1MAPTSMN1; SMN2GAA
SCHEMBL1857666 0.87 ALDH1A1 (0.56) MAOBALDH1A1MAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6575859-B2 A belt tension adjusting device comprising a stationary fulcrum shaft, an arm pivotally supported on said fulcrum shaft through a slide bearing formed of a synthetic resin, a tension pulley mounted on said arm at one end thereof for NTN CORPORATION (JP) 2003-06-10 US disclosed
US-6513986-B2 Electrical pittingproof rolling bearing NTN CORPORATION (JP) 2003-02-04 US disclosed
US-20010021679-A1 Belt tension adjusting device NTN CORPORATION (JP) 2001-09-13 US disclosed
US-20010014545-A1 Electrical pittingproof rolling bearing NTN CORPORATION (JP) 2001-08-16 US disclosed
US-5900453-A BLEND OF POLYIMIDE, POLYTETRAFLUOROETHYLENE AND AROMATIC POLYESTER NTN CORPORATION (JP) 1999-05-04 US disclosed
EP-0633294-B1 Polyimide based resin composition MITSUI CHEMICALS INC (JP) 1998-06-10 EP disclosed
US-5726232-A TETRAFLUOROETHYLENE POLYMER, LITHIUM PHOSPHATE NTN CORPORATION (JP) 1998-03-10 US disclosed
EP-0591551-B1 POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1998-03-04 EP disclosed
EP-0812885-A2 Polyimide based resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-12-17 EP disclosed
US-5650463-A Carbon fiber-reinforced polimide resin composition MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-22 US disclosed
US-5013848-A Heat resistant thermosetting polymer with impact strength and flexibility MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1991-05-07 US disclosed
EP-0253891-B1 AROMATIC BISMALEIMIDO COMPOUNDS AND PROCESS FOR THEIR PREPARATION MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-03 EP disclosed
US-4994544-A Imidation of polyamic acids MITSUI TOATSU CHEMICALS, INC. (JP) 1991-02-19 US disclosed
US-4937316-A Process for preparing polyimides AMDAHL CORPORATION (US) 1990-06-26 US disclosed
EP-0368590-A2 Production process for polyimide fibers MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-16 EP disclosed
EP-0350203-A2 Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-10 EP disclosed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP disclosed
EP-0313407-A2 Method for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-26 EP disclosed
EP-0253891-A1 AROMATIC BISMALEIMIDO COMPOUNDS AND PROCESS FOR THEIR PREPARATION MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-01-27 EP disclosed
EP-0192480-A1 Bis(3-aminophenoxy) aromatics and method of preparing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-08-27 EP disclosed