SCHEMBL6933749

SCHEMBL6933749

Cc1cc(C(C)(C)c2ccc(Oc3cccc(N)c3)c(C)c2)ccc1Oc1cccc(N)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.47
ALDH1A1 P00352 6/20 0.44
CYP3A4 P08684 2/20 0.44
MAPT P10636 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
POLB P06746 1/20 0.42
HSP90AA1 P07900 1/20 0.42
TP53 P04637 1/20 0.41
GAA P10253 2/20 0.41
ATM Q13315 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ESR1 P03372 2/20 0.37
MEN1 O00255 1/20 0.37
MITF O75030 1/20 0.37
GFER P55789 1/20 0.37
KMT2A Q03164 1/20 0.37
NLRP1 Q9C000 1/20 0.37
NOD2 Q9HC29 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6932613 0.94 MAOB (0.50) MAOBALDH1A1CYP3A4MAPTL3MBTL1
SCHEMBL7569937 0.85 MAOB (0.55) MAOBALDH1A1CYP3A4MAPTL3MBTL1
SCHEMBL9576142 0.85 ALDH1A1 (0.47) MAOBALDH1A1CYP3A4MAPTL3MBTL1
SCHEMBL1855632 0.84 ALDH1A1 (0.42) ALDH1A1MAPTL3MBTL1NPSR1POLB
SCHEMBL29393830 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4MAPTL3MBTL1POLB
SCHEMBL1856220 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4MAPTL3MBTL1POLB
SCHEMBL29535518 0.82 ALDH1A1 (0.55) ALDH1A1CYP3A4MAPTL3MBTL1POLB
SCHEMBL5604536 0.82 MAOB (0.52) MAOBALDH1A1CYP3A4MAPTL3MBTL1
SCHEMBL30994908 0.82 MAOB (0.52) MAOBALDH1A1CYP3A4MAPTL3MBTL1
SCHEMBL26102576 0.82 MAOB (0.52) MAOBALDH1A1CYP3A4MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6575859-B2 A belt tension adjusting device comprising a stationary fulcrum shaft, an arm pivotally supported on said fulcrum shaft through a slide bearing formed of a synthetic resin, a tension pulley mounted on said arm at one end thereof for NTN CORPORATION (JP) 2003-06-10 US disclosed
US-6513986-B2 Electrical pittingproof rolling bearing NTN CORPORATION (JP) 2003-02-04 US disclosed
US-20010021679-A1 Belt tension adjusting device NTN CORPORATION (JP) 2001-09-13 US disclosed
US-20010014545-A1 Electrical pittingproof rolling bearing NTN CORPORATION (JP) 2001-08-16 US disclosed
US-5900453-A BLEND OF POLYIMIDE, POLYTETRAFLUOROETHYLENE AND AROMATIC POLYESTER NTN CORPORATION (JP) 1999-05-04 US disclosed
EP-0633294-B1 Polyimide based resin composition MITSUI CHEMICALS INC (JP) 1998-06-10 EP disclosed
US-5726232-A TETRAFLUOROETHYLENE POLYMER, LITHIUM PHOSPHATE NTN CORPORATION (JP) 1998-03-10 US disclosed
EP-0591551-B1 POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1998-03-04 EP disclosed
EP-0812885-A2 Polyimide based resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-12-17 EP disclosed
US-5650463-A Carbon fiber-reinforced polimide resin composition MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-22 US disclosed
EP-0253891-B1 AROMATIC BISMALEIMIDO COMPOUNDS AND PROCESS FOR THEIR PREPARATION MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-03 EP disclosed
US-4994544-A Imidation of polyamic acids MITSUI TOATSU CHEMICALS, INC. (JP) 1991-02-19 US disclosed
EP-0368590-A2 Production process for polyimide fibers MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-16 EP disclosed
EP-0350203-A2 Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-10 EP disclosed
EP-0330505-A1 Process for preparing polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP disclosed
EP-0313407-A2 Method for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-26 EP disclosed
EP-0292243-A2 Heat resistant resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-11-23 EP disclosed
EP-0253891-A1 AROMATIC BISMALEIMIDO COMPOUNDS AND PROCESS FOR THEIR PREPARATION MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-01-27 EP disclosed
EP-0192480-A1 Bis(3-aminophenoxy) aromatics and method of preparing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-08-27 EP disclosed