Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932695 | 1.00 | ANPEP (0.47) | ANPEPSLC18A3IDO1SIGMAR1ACHE | |
| SCHEMBL172863 | 1.00 | ANPEP (0.47) | ANPEPSLC18A3IDO1SIGMAR1ACHE | |
| SCHEMBL29687690 | 0.82 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1 | |
| SCHEMBL1990443 | 0.82 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1 | |
| SCHEMBL1990446 | 0.82 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1 | |
| SCHEMBL31236844 | 0.82 | IDO1 (0.46) | IDO1ACHE | |
| SCHEMBL31236843 | 0.82 | IDO1 (0.46) | IDO1ACHE | |
| SCHEMBL20095994 | 0.82 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1 | |
| SCHEMBL20063792 | 0.82 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1 | |
| Naphthalene SCHEMBL8201172 | 0.75 | ANPEP (0.50) | ANPEPSLC18A3IDO1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083889-B1 | TETRAHYDRONAPHTALENE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ORTHO MCNEIL PHARM INC (US) | 2003-12-10 | — | — | EP | disclosed |