SCHEMBL1990446

SCHEMBL1990446

OC1Cc2ccccc2CC1O

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.56
SLC18A3 Q16572 3/20 0.47
IDO1 P14902 2/20 0.46
SIGMAR1 Q99720 1/20 0.43
PLAU P00749 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20063792 1.00 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1PLAU
SCHEMBL29687690 1.00 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1PLAU
SCHEMBL20095994 1.00 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1PLAU
SCHEMBL1990443 1.00 ANPEP (0.56) ANPEPSLC18A3IDO1SIGMAR1PLAU
Naphthalene SCHEMBL8201172 0.92 ANPEP (0.50) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL6932695 0.82 ANPEP (0.47) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL11355392 0.82 ANPEP (0.68) ANPEPSLC18A3IDO1PLAU
SCHEMBL22893170 0.82 ANPEP (0.47) ANPEPSLC18A3IDO1SIGMAR1
SCHEMBL3996873 0.82 ANPEP (0.68) ANPEPSLC18A3IDO1PLAU
SCHEMBL9515317 0.82 ANPEP (0.68) ANPEPSLC18A3IDO1PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2500407-B1 Cleaning formulations and method of using the cleaning formulations AIR PROD & CHEM (US) 2017-07-19 EP claimed
WO-2000022662-A1 INHIBITION OF TITANIUM CORROSION EKC TECHNOLOGY, LTD (GB) 2000-04-20 WO claimed
US-20250381198-A1 MIDAZOLAM AND KETAMINE FOR ENHANCED SEDATION FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-12-18 US disclosed
US-20240415848-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2024-12-19 US disclosed
US-12083126-B2 Pharmaceutical compositions and methods for anesthesiological applications MELT PHARMACEUTICALS, INC. (US) 2024-09-10 US disclosed
CN-111712241-B Sigma-1 receptor agonist systolic blood pressure therapy 阿纳韦克斯生命科学公司 2024-02-13 CN disclosed
US-20220249510-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2022-08-11 US disclosed
US-20220031664-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTIEMETICS AND ALPHA-2-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USING THE SAME FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2022-02-03 US disclosed
US-20210085691-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2021-03-25 US disclosed
US-20200297734-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2020-09-24 US disclosed
US-10391102-B2 Pharmaceutical compositions and methods for anesthesiological applications MELT PHARMACEUTICALS, INC. (US) 2019-08-27 US disclosed
WO-2012171114-A1 SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2012-12-20 WO disclosed
US-20110152210-A1 POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2011-06-23 US disclosed
EP-1934159-B1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS BASF SE (DE) 2009-03-25 EP disclosed
US-20090030235-A1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS BASF SE (DE) 2009-01-29 US disclosed
WO-2000022662-A1 INHIBITION OF TITANIUM CORROSION EKC TECHNOLOGY, LTD (GB) 2000-04-20 WO disclosed
WO-2000022662-A1 INHIBITION OF TITANIUM CORROSION EKC TECHNOLOGY, LTD (GB) 2000-04-20 WO disclosed
EP-0145447-A1 Process for epoxidizing vicinal diols EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-06-19 EP disclosed
US-4111917-A POLYURETHANES W. R. GRACE & CO. (US) 1978-09-05 US disclosed
US-4029676-A ANTIADRENERGIC, ANTIFIBRILLATORY E. R. SQUIBB & SONS, INC. (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220249510-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS GRIN3A, OPRK1, GRIN2B ANPEP 2857/4885SLC18A3 399/4885IDO1 1142/4885
US-10391102-B2 Pharmaceutical compositions and methods for anesthesiological applications GRIN2B, GRIN3A, GABRA5 ANPEP 2849/4885SLC18A3 780/4885IDO1 896/4885
US-20240415848-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS GRIN3A, OPRK1, GRIN2B ANPEP 2857/4885SLC18A3 399/4885IDO1 1142/4885
US-20200297734-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS GRIN3A, OPRK1, GRIN2B ANPEP 2857/4885SLC18A3 399/4885IDO1 1142/4885
US-20210085691-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR ANESTHESIOLOGICAL APPLICATIONS GRIN2B, GRIN3A, GRIN1 ANPEP 2211/4885SLC18A3 471/4885IDO1 869/4885
US-20250381198-A1 MIDAZOLAM AND KETAMINE FOR ENHANCED SEDATION KCNA3, OPRK1, KCNA7 ANPEP 3405/4885SLC18A3 335/4885IDO1 2848/4885
US-20090030235-A1 METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS ADH5, ADH1C, ADH1A ANPEP 710/4885SLC18A3 784/4885IDO1 2146/4885
US-12083126-B2 Pharmaceutical compositions and methods for anesthesiological applications GRIN3A, OPRK1, GRIN2B ANPEP 2857/4885SLC18A3 399/4885IDO1 1142/4885
US-20110152210-A1 POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF PSMC1, PSME1, PSMB1 ANPEP 1096/4885SLC18A3 4526/4885IDO1 3112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.