Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20063792 | 1.00 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1PLAU | |
| SCHEMBL29687690 | 1.00 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1PLAU | |
| SCHEMBL20095994 | 1.00 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1PLAU | |
| SCHEMBL1990446 | 1.00 | ANPEP (0.56) | ANPEPSLC18A3IDO1SIGMAR1PLAU | |
| Naphthalene SCHEMBL8201172 | 0.92 | ANPEP (0.50) | ANPEPSLC18A3IDO1SIGMAR1 | |
| SCHEMBL6932695 | 0.82 | ANPEP (0.47) | ANPEPSLC18A3IDO1SIGMAR1 | |
| SCHEMBL11355392 | 0.82 | ANPEP (0.68) | ANPEPSLC18A3IDO1PLAU | |
| SCHEMBL22893170 | 0.82 | ANPEP (0.47) | ANPEPSLC18A3IDO1SIGMAR1 | |
| SCHEMBL3996873 | 0.82 | ANPEP (0.68) | ANPEPSLC18A3IDO1PLAU | |
| SCHEMBL9515317 | 0.82 | ANPEP (0.68) | ANPEPSLC18A3IDO1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378541-A1 | Synthetic Epigallocatechin Gallate (EGCG) Analogs | WAYNE STATE UNIVERSITY (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140378541-A1 | Synthetic Epigallocatechin Gallate (EGCG) Analogs | WAYNE STATE UNIVERSITY (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140378541-A1 | Synthetic Epigallocatechin Gallate (EGCG) Analogs | WAYNE STATE UNIVERSITY (US) | 2014-12-25 | — | — | US | disclosed |
| EP-2721000-A1 | SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2014-04-23 | — | — | EP | disclosed |
| WO-2012171114-A1 | SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012171114-A1 | SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-12-20 | — | — | WO | disclosed |
| US-20110152210-A1 | POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2011-06-23 | — | — | US | disclosed |
| US-20110152210-A1 | POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2011-06-23 | — | — | US | disclosed |
| US-20110152210-A1 | POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378541-A1 | Synthetic Epigallocatechin Gallate (EGCG) Analogs | GLS2, GLS, PC | ANPEP 2428/4885SLC18A3 3084/4885IDO1 3865/4885 |
| US-20110152210-A1 | POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF | PSMC1, PSME1, PSMB1 | ANPEP 1096/4885SLC18A3 4526/4885IDO1 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.