Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 7/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30674534 | 0.85 | HRH3 (0.55) | HRH3LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5494073 | 0.81 | EED (0.47) | NPY1RHRH3EED | |
| SCHEMBL28283793 | 0.80 | NPY1R (0.57) | NPY1R | |
| SCHEMBL30556335 | 0.79 | ACP1 (0.47) | NPY1REED | |
| SCHEMBL30674514 | 0.78 | HRH3 (0.54) | HRH3LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL6632458 | 0.78 | EED (0.44) | NPY1REED | |
| SCHEMBL8971574 | 0.76 | EED (0.46) | NPY1RLMNAEED | |
| SCHEMBL31071592 | 0.76 | SLC6A2 (0.63) | — | |
| SCHEMBL11715794 | 0.75 | NPY1R (0.42) | NPY1REED | |
| SCHEMBL11448870 | 0.75 | LMNA (0.50) | HRH3LMNAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319004-A2 | SUBSTITUTED AZEPINO[4,5-B]INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024701-A2 | SUBSTITUTED AZEPINO[4,5B)INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |