SCHEMBL6933080

SCHEMBL6933080

Cc1c(CCO)sc[n+]1Cc1c(Cl)cccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TKT P29401 16/20 0.55
HSP90AA1 P07900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3845516 0.99 TKT (0.56) TKTHSP90AA1
SCHEMBL2900332 0.78 TKT (0.61) TKTHSP90AA1
Bromide SCHEMBL3851471 0.77 TKT (0.40) TKT
Hydrochloric Acid SCHEMBL29995247 0.77 TKT (0.60) TKTHSP90AA1
Bromide SCHEMBL7625997 0.77 TKT (0.60) TKTHSP90AA1
Hydrochloric Acid SCHEMBL21337 0.77 LMNA (0.63) TKTHSP90AA1
SCHEMBL13741511 0.73 TKT (0.69) TKTHSP90AA1
SCHEMBL13741493 0.73 TKT (0.73) TKTHSP90AA1
Bromide SCHEMBL8941023 0.73 TKT (0.54) TKTHSP90AA1
SCHEMBL2026240 0.73 TKT (0.54) TKTHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808163-B1 USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS ALTEON INC (US) 2003-07-23 EP claimed
US-6440749-B1 ADMINISTERING A THIAZOLE COMPOUND ALTEON. INC. 2002-08-27 US claimed