Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 14/20 | 0.73 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939875 | 0.97 | ADA (0.78) | ADAMTNR1AMTNR1BNQO2ADRB2 | |
| SCHEMBL6940653 | 0.91 | ADA (0.78) | ADA | |
| SCHEMBL6941851 | 0.89 | ADA (0.79) | ADAADRB2 | |
| SCHEMBL6936287 | 0.87 | ADA (0.95) | ADA | |
| SCHEMBL6933256 | 0.86 | ADA (0.54) | ADA | |
| SCHEMBL6939869 | 0.84 | ADA (1.00) | ADA | |
| SCHEMBL6938860 | 0.83 | ADA (0.72) | ADAMTNR1AMTNR1BNQO2GRK2 | |
| SCHEMBL6941961 | 0.83 | ADA (0.53) | ADAMEN1KMT2A | |
| SCHEMBL6941521 | 0.80 | ADA (0.60) | ADA | |
| SCHEMBL6938856 | 0.79 | ADA (0.80) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |