Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3848882 | 0.99 | OPRM1 (0.52) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| SCHEMBL6937914 | 0.85 | OPRM1 (0.61) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| Bromide SCHEMBL2947503 | 0.84 | OPRM1 (0.64) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| Bromide SCHEMBL3848606 | 0.83 | KMT2A (0.64) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| SCHEMBL6103657 | 0.81 | POLB (0.48) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| SCHEMBL6935373 | 0.81 | OPRM1 (0.52) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| Bromide SCHEMBL3846880 | 0.81 | POLB (0.50) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| SCHEMBL6935005 | 0.80 | MITF (0.55) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| SCHEMBL6939126 | 0.80 | KMT2A (0.67) | OPRM1OPRD1MAPTNPSR1KMT2A | |
| Bromide SCHEMBL3844426 | 0.80 | OPRM1 (0.53) | OPRM1OPRD1MAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808163-B1 | USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC (US) | 2003-07-23 | — | — | EP | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | claimed |
| US-6440749-B1 | ADMINISTERING A THIAZOLE COMPOUND | ALTEON. INC. | 2002-08-27 | — | — | US | disclosed |