Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936496 | 0.95 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL4240942 | 0.89 | FFAR1 (0.52) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL6938030 | 0.89 | FFAR1 (0.53) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL5886652 | 0.87 | FFAR1 (0.63) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL15921659 | 0.87 | FFAR1 (0.69) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL6932038 | 0.85 | FFAR1 (0.52) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL2023915 | 0.84 | FFAR1 (0.70) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL9333090 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL9332907 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL9335934 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4MMP2MMP12TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118556-A2 | SELECTIVE INHIBITORS AND ALLOSTERIC ACTIVATORS OF SPHINGOSINE KINASE | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2014-08-07 | — | — | WO | disclosed |
| EP-0962445-B1 | Acetylene compound, liquid crystal composition and liquid crystal element | MITSUI CHEMICALS INC (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-6217793-B1 | Acetylene compound, liquid crystal composition and liquid crystal element | MITSUI CHEMICALS, INC. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0962445-A1 | Acetylene compound, liquid crystal composition and liquid crystal element | Mitsui Chemicals, Inc. (JP) | 1999-12-08 | — | — | EP | disclosed |
| EP-0195097-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | disclosed |
| US-4699995-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. (GB) | 1987-10-13 | — | — | US | disclosed |
| EP-0142145-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1987-03-04 | — | — | EP | disclosed |
| EP-0195097-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1986-09-24 | — | — | EP | disclosed |
| EP-0142145-A2 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1985-05-22 | — | — | EP | disclosed |