SCHEMBL6932038

SCHEMBL6932038

CCCCCCCCC#Cc1ccc2cc(CO)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.52
FFAR4 Q5NUL3 1/20 0.52
MMP2 P08253 1/20 0.45
MMP12 P39900 1/20 0.45
KCNH2 Q12809 1/20 0.40
PRKCA P17252 3/20 0.40
TNK2 Q07912 1/20 0.39
PRKCG P05129 2/20 0.39
PRKCB P05771 2/20 0.39
PRKCE Q02156 2/20 0.39
PRKCD Q05655 2/20 0.39
GPR84 Q9NQS5 1/20 0.38
BDKRB2 P30411 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933475 0.85 FFAR1 (0.64) FFAR1FFAR4MMP2MMP12KCNH2
SCHEMBL10754443 0.82 KCNH2 (0.49) FFAR1FFAR4MMP2MMP12KCNH2
SCHEMBL5886619 0.82 KCNH2 (0.47) FFAR1FFAR4MMP2MMP12KCNH2
SCHEMBL6936496 0.81 FFAR1 (0.59) FFAR1FFAR4MMP2MMP12KCNH2
SCHEMBL16151309 0.81 KCNH2 (0.46) FFAR1FFAR4MMP2MMP12KCNH2
SCHEMBL6937097 0.78 MMP2 (0.59) FFAR1FFAR4MMP2MMP12
SCHEMBL2806992 0.78 MMP2 (0.59) FFAR1FFAR4MMP2MMP12
SCHEMBL6938030 0.78 FFAR1 (0.53) FFAR1FFAR4MMP2MMP12TNK2
SCHEMBL7337990 0.76 MMP2 (0.56) FFAR1FFAR4MMP2MMP12
SCHEMBL15921659 0.76 FFAR1 (0.69) FFAR1FFAR4MMP2MMP12KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962445-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS INC (JP) 2003-02-26 EP disclosed
US-6217793-B1 Acetylene compound, liquid crystal composition and liquid crystal element MITSUI CHEMICALS, INC. (JP) 2001-04-17 US disclosed
EP-0962445-A1 Acetylene compound, liquid crystal composition and liquid crystal element Mitsui Chemicals, Inc. (JP) 1999-12-08 EP disclosed