Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.61 |
| ▸ | NQO2 | P16083 | 2/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12510798 | 1.00 | TLR8 (0.61) | TLR8NQO2GPBAR1MCHR1MAPT | |
| SCHEMBL2246934 | 0.84 | TLR8 (0.50) | TLR8MCHR1MAPTLMNACYP3A4 | |
| SCHEMBL6933511 | 0.84 | TLR8 (0.50) | TLR8MCHR1MAPTLMNACYP3A4 | |
| SCHEMBL2367661 | 0.83 | TLR8 (0.54) | TLR8MCHR1MAPTLMNACYP3A4 | |
| SCHEMBL346563 | 0.82 | TLR8 (0.64) | TLR8GPBAR1MCHR1MAPTLMNA | |
| SCHEMBL2368024 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1NPC1HPGD | |
| SCHEMBL28002627 | 0.80 | TLR8 (0.54) | TLR8GPBAR1MAPTLMNACYP3A4 | |
| SCHEMBL31290761 | 0.80 | TLR8 (0.63) | TLR8GPBAR1MCHR1MAPTLMNA | |
| SCHEMBL4250155 | 0.79 | TLR8 (0.60) | TLR8GPBAR1MCHR1MAPTLMNA | |
| SCHEMBL30844101 | 0.79 | TLR8 (0.60) | TLR8GPBAR1MCHR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | claimed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | claimed |
| US-8552086-B2 | Dental compositions including organogelators, products, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-8552086-B2 | Dental compositions including organogelators, products, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-8445558-B2 | Dental compositions including organogelators, products, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-21 | — | — | US | disclosed |
| US-8445558-B2 | Dental compositions including organogelators, products, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20130109780-A1 | DENTAL COMPOSITIONS INLCUDING ORGANOGELATORS, PRODUCTS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109780-A1 | DENTAL COMPOSITIONS INLCUDING ORGANOGELATORS, PRODUCTS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |
| EP-2073782-B1 | DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2011-07-20 | — | — | EP | disclosed |
| US-20090305196-A1 | DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2009-12-10 | — | — | US | disclosed |
| US-20090305196-A1 | DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2009-12-10 | — | — | US | disclosed |
| WO-2008033911-A2 | DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109780-A1 | DENTAL COMPOSITIONS INLCUDING ORGANOGELATORS, PRODUCTS, AND METHODS | ILK, EPM2A, PDE6G | TLR8 3890/4885NQO2 2682/4885GPBAR1 4255/4885 |
| US-20090305196-A1 | DENTAL COMPOSITIONS INCLUDING ORGANOGELATORS, PRODUCTS, AND METHODS | DDOST, DNA2, KRTCAP2 | TLR8 4193/4885NQO2 2534/4885GPBAR1 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.