Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 8/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FSHR | P23945 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217536 | 0.89 | LHCGR (0.63) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL6217498 | 0.89 | LHCGR (0.62) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL6217036 | 0.88 | LHCGR (0.61) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL6218440 | 0.88 | LHCGR (0.61) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL6931327 | 0.87 | LHCGR (0.61) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL4327613 | 0.86 | LHCGR (0.77) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL6218002 | 0.85 | LHCGR (0.58) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL6220445 | 0.84 | LHCGR (0.65) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL6216201 | 0.83 | LHCGR (0.56) | LHCGRTSHRKDM4EMAPTALDH1A1 | |
| SCHEMBL4431522 | 0.83 | LHCGR (0.62) | LHCGRTSHRKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569863-B1 | Luteinizing hormone (LH) agonists for controlling fertility | AKZO NOBEL NV (NL) | 2003-05-27 | — | — | US | disclosed |